De Morbis Universalibus et Particularibus, Libri IV. Posteriores Pathologiae. Adjecta est singulorum morborum praesidendi, curandique ratio Fernel, Jean (Ioan Fernelius) Medicine

A cornerstone of Renaissance and early modern medical literature, this is Jean Fernelâ s seminal treatise on pathology, published posthumously in Leiden by the noted printer Franciscus Hackius. Often referred to as the father of modern physiology, Fernel (1497â "1558) advanced the idea that diseases arise from specific pathological causes rather than vague imbalancesâ "an early and influential step toward scientific medicine. In De Morbis Universalibus et Particularibus, he explores fevers, infections, disorders of the senses, and external ailments, merging classical Galenic theory with empirical observation. This 1645 Leiden edition represents one of the finest early modern printings of Fernelâ s Pathologia, richly detailed and foundational for understanding how pre-modern physicians categorized and treated disease. The work is illustrated with an elaborate engraved title page showing a Renaissance medical sceneâ "Fernel lecturing before a group of physicians examining patients, set within an architectural interior. The engraving is attributed to Cornelis van Dalen, who worked for Hackius during this period, though it is unsigned. The volume exhibits the hallmarks of scholarly 17th-century typography, with italic marginalia and carefully structured sections on fevers (De Febribus), external afflictions, and chronic disorders. Condition: Interior remarkably clean with minor age toning, scattered foxing, and occasional early marginal notes. Light dampstaining to upper margins of a few leaves, but sound and tight overall. A solid, unrestored example in original binding, typical of scholarly use. Overall good to very good. Contemporary full mottled calf, double gilt fillet borders, raised bands on spine. Spine worn with chipping to head and tail, joints rubbed, corners softened; gilt titles and compartments faint but visible