Opera Omnia, Tomus Prior Willis, Thomas Anatomy,Biology,Medicine,Science

A landmark volume in early modern medical science: the first collected edition of Thomas Willisâ s Opera Omnia, printed in Geneva by Samuel de Tournes in 1680. This is Tomus Prior, the first of two volumes, containing several of Willisâ s most influential treatises, including De Fermentatione, De Febribus, De Urinis, Cerebri Anatome, and De Ratione Motus Musculorum. The work consolidates the writings of one of the founding figures of neurology and experimental physiology, renowned for identifying the â Circle of Willisâ in the brain and pioneering studies on the nervous system. Illustrated with engraved folding anatomical plates, this edition was among the first to systematize human neurological anatomy and establish the relationship between the brain, nerves, and bodily motion. The text, in Latin, opens with the printerâ s dedication, typographic ornaments, and a detailed â Contenta in Priori Tomoâ listing Willisâ s major contributions to anatomy, pathology, and natural philosophy. The folding plates display intricate copper engravings of the nervous system and musculature, among the earliest scientific renderings of their kind. A significant example of 17th-century medical publishing, this volume bridges Renaissance anatomy and Enlightenment physiology. An early ink ownership inscription and marginal annotations suggest scholarly use, adding to its research and provenance interest. Condition & Binding: Contemporary full calf, gilt-tooled spine in six compartments with floral devices and gilt titling reading WILLIS OPERA TOM. I. The binding is heavily worn and partially perished, with both joints cracked and the spine leather largely detached, revealing cords and sewing structure beneath. Boards show substantial surface wear, scuffing, and losses to corners and edges. Interior exhibits moderate to heavy foxing and waterstaining, particularly near the beginning and end of the volume, though text remains clear and legible. Several folding engraved plates present, one with old repairs and small marginal tears. Evidence of early handwritten notes to the front endpaper, likely 18th-century scholarly references. Despite its rough exterior, the book remains complete and structurally sound. Overall- fair.