Handbook of Animal Models and Its Uses in Cancer Research (Hardcover)

This reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression formation and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering including CRISP/Cas9 in designing and developing animal models for cancer research. Further it discusses strategies for modeling animals for investigating growth metastasis tumor-associated inflammation and microenvironment cancer stem cells tumor heterogeneity and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers clinicians and health care.