Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds (Paperback)

This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals agrochemicals electronics food flavour and fragrance industries are all represented. Chirality in Industry II All new case histories Unique industrial perspective on chiral technology Emphasis on scale-up and process development Comparison of biocatalysis asymmetric synthesis and classical resolution approaches The chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple elegant solution.