Gene Environment Interactions: Nature and Nurture in the Twenty-First Century (Paperback)

Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare synergistic view of ongoing revelations in gene environment interaction studies drawing together key themes from epigenetics microbiomics disease etiology and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters Dr. Smith discusses interactions with the environment human adaptations to environmental stimuli pathogen encounters across the centuries epigenetic modulation of gene expression transgenerational inheritance the microbiome s intrinsic effects on human health and the gene-environment etiology of cardiovascular metabolic psychiatric behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition the book s author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.